Does tranexamic acid have its place in the prevention of postpartum hemorrhage?

1. Anaesth Crit Care Pain Med. 2023 Aug;42(4):101241. doi:
10.1016/j.accpm.2023.101241. Epub 2023 May 11.

Does tranexamic acid have its place in the prevention of postpartum hemorrhage?

Bouvet L(1), Rackelboom T(2), Bouthors AS(3), Morau E(4); CARO working group.

Collaborators: Sophie Baptiste A(5), Benhamou D(6), Pierre Bonnet M(7), Bonnin
M(8), Sophie Bouthors A(9), Bouvet L(1), Chassard D(1), Yves Dewandre P(10),
Fisher C(11), Gonzalez M(12), Julliac B(13), Keita H(14), Le Gouez A(15),
Mercier FJ(16), Morau E(17), Rackelboom T(18), Vial F(19).

Author information:
(1)Department of Anesthesiology and Critical Care, Groupement Hospitalier Est,
Hôpital Femme Mère Enfant, Hospices Civils de Lyon, Lyon, France.
(2)Department of Anesthesiology Intensive Care and Perioperative Medicine, CHU
de Bordeaux, Bordeaux, France.
(3)Department of Anesthesiology and Critical Care, Jeanne de Flandre Women’s
Hospital, Academic Hospital, 59037 Lille, France; Univ. Lille, ULR 7365 – GRITA
– Groupe de Recherche sur les formes Injectables et les Technologies Associées,
F-59000 Lille, France.
(4)Department of Anesthesia, Intensive Care and Perioperative Medicine, CHU
Nîmes, Nîmes, France. Electronic address: estelle.morau@chu-nimes.fr.
(5)Department of Anesthesia, Hôpital de Roubaix, France.
(6)Department of Anesthesia, Intensive Care and Perioperative Medicine AP-HP,
Université Paris Saclay, Hôpital Bicêtre, Paris, France.
(7)Department of Anesthesiology and Critical Care, Hôpital Armand Trousseau, DMU
DREAM, Assistance Publique des Hôpitaux de Paris, France; Université de Paris,
Centre for Epidemiology and Statistics Sorbonne Paris Cité (CRESS), Obstetrical
Perinatal and Pediatric Epidemiology Research Team, EPOPE, INSERM, INRA, Paris,
France.
(8)Department of Anesthesia and Critical Care Medicine, Pôle
Anesthesie-Reanimation-Estaing, Clermont-Ferrand, France.
(9)Department of Anesthesiology and Critical Care, Jeanne de Flandre Women’s
Hospital, Academic hospital, 59037 Lille France; Univ. Lille, ULR 7365 – GRITA –
Groupe de Recherche sur les formes Injectables et les Technologies Associées,
F-59000 Lille, France.
(10)Department of Anesthesiology and Critical Care Liège, Belgique.
(11)Department of Anesthesiology and Critical Care, Hôpital Cochin-Port Royal,
AP-HP, Paris, France.
(12)Department of Anesthesiology and Critical Care, Jeanne de Flandre Women’s
Hospital.
(13)Department of Anesthesiology and Critical Care, Maison de Santé protestante
de Bagatelle, Bordeaux France.
(14)Department of Anesthesiology and Critical Care, Hôpital
Necker-Enfants-Malades, AP-HP; Centre – Université de Paris, France, Unité de
Recherche EA 7323 Pharmacologie et Evaluation des Thérapeutiques Chez l’Enfant
et la Femme Enceinte, Université de Paris, France.
(15)Department of Anesthesia and Critical Care Medicine, Hôpital Antoine
Béclère, AP-HP, Clamart, France.
(16)Department of Anesthesia and Critical Care Medicine, Hôpital Antoine
Béclère, AP-HP. Université Paris-Saclay, Clamart, France.
(17)Department of Anaesthesia Intensive Care and Perioperative Medicine, CHU
Nimes, Nîmes, France.
(18)Department of Anaesthesia Intensive Care and Perioperative Medicine, CHU de
Bordeaux, Bordeaux, France.
(19)Department of Anesthesia and Critical Care Medicine CHRU Nancy, Nancy.

DOI: 10.1016/j.accpm.2023.101241
PMID: 37178818 [Indexed for MEDLINE]